A Study to Compare the Pharmacokinetic Characteristics of CJ-12420

A Randomized, Open-label, Single Dose, Crossover Study to Compare the Pharmacokinetic Characteristics of CJ-12420 in Healthy Male Volunteers

To compare the pharmacokinetics after administration of different formulation of CJ-12420

The purpose of this study is to compare the pharmacokinetics after a single dose administration of CJ-12420 formulation 1 and formulation 2.

Inclusion Criteria:

• Healthy male aged 19 to 45 years at the screening
• Subject who is over 50kg with BMI between 19 kg/m2 to 28 kg/m2 (inclusive)
• Subject who fully understood after being informed detailed description of clinical trial, written informed consent voluntarily to observe the precautions.

Exclusion Criteria:

• Subject who fall under the criteria below in laboratory test.

  • AST, ALT, ALP, GGT, total bilirubin, BUN, creatinine > UNL x 1.5

• Subject who with low blood pressure with clinical significance at screening test.

  • (systolic blood pressure is less than 90 mmHg or over 140 mmHg, and diastolic blood pressure is less than 50 mmHg or over 90 mmHg)

• Subject who has a medical history of symptomatic GERD, erosive esophagitis or duodenal ulcer, gastric ulcer, barrett's esophagus or zollinger-ellison syndrome.