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| Name | Class |
|---|---|
| Seoul National University Hospital | OTHER |
| Samsung Medical Center | OTHER |
| Asan Medical Center | OTHER |
| Seoul National University Bundang Hospital |
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The purpose of this study is to investigate risk factors for mediastinal lymph node metastasis in potentially operable non-small cell lung cancer in order to find indications for endoscopic mediastinal staging. Chest CT, integrated PET/CT, and endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) +/- endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) are performed for mediastinal staging. CT and PET/CT findings, histologic types and other risk factors will be analyzed. The investigators develop the prediction method for mediastinal metastasis.
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| Measure | Description | Time Frame |
|---|---|---|
| Relative risk of risk factors for mediastinal metastasis | risk factors; CT staging (N0-3), PET staging (N0-3), tumor location(central or peripheral), tumor size and histologic types of lung cancer. | When confirmative diagnosis are available in all subjects ;3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic values of endoscopic staging | sensitivity, negative predictive value, accuracy | When confirmative diagnosis are available in all subjects ;3 years |
| Survival | survival after lung cancer treatment |
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Inclusion Criteria:
Exclusion Criteria:
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Non-small cell lung cancer
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| Name | Affiliation | Role |
|---|---|---|
| Bin Hwangbo, PhD | National Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Center (NCC) Korea | Goyang-si | Gyeonggi-do | 410-769 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37019355 | Derived | Chung HS, Yoon HI, Hwangbo B, Park EY, Choi CM, Park YS, Lee K, Ji W, Park S, Lee GK, Kim TS, Kim HY, Kim MS, Lee JM. Prediction Models for Mediastinal Metastasis and Its Detection by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Potentially Operable Non-Small Cell Lung Cancer: A Prospective Study. Chest. 2023 Sep;164(3):770-784. doi: 10.1016/j.chest.2023.03.041. Epub 2023 Apr 3. |
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| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
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| OTHER |
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| After the diagnosis ; 7 years |
| Molecular test | EGFR, ALK etc | for each subject; up to 60 days, available in all subjects ; 3 years |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |