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The purpose of this study is to investigate the effects of daily supplementation of OLECOL for a period of 8 weeks on cardiovascular risk markers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| OLECOL | Active Comparator | Olive leaf extract |
|
| Placebo | Placebo Comparator | Maltodextrin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OLECOL | Dietary Supplement | Olive leaf extract |
| |
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Blood lipid profile | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Lipid peroxidation | 8 weeks | |
| Glucose metabolism | 8 weeks | |
| Systolic and diastolic blood pressure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ad Masclee, MD | Maastricht University Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maastricht University Medical Center | Maastricht | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33034707 | Derived | Stevens Y, Winkens B, Jonkers D, Masclee A. The effect of olive leaf extract on cardiovascular health markers: a randomized placebo-controlled clinical trial. Eur J Nutr. 2021 Jun;60(4):2111-2120. doi: 10.1007/s00394-020-02397-9. Epub 2020 Oct 9. |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| D006937 | Hypercholesterolemia |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| Dietary Supplement |
Maltodextrin |
|
| 8 weeks |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006949 | Hyperlipidemias |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |