The Effect of Olive Leaf Extract Administration on Cardiovascular Health

The Effect of Olive Leaf Extract Administration on Cardiovascular Health

The purpose of this study is to investigate the effects of daily supplementation of OLECOL for a period of 8 weeks on cardiovascular risk markers.

Inclusion Criteria:

• Healthy individuals
• Age between 18 and 70 years
• Total cholesterol levels ≥ 5.0 mmol/L
• BMI 25-35 kg/m2

Exclusion Criteria:

• History of severe cardiovascular, respiratory, urogenital, gastrointestinal/hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat). Dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological diseases, allergy, major surgery and /or laboratory assessments that might limit participation in or completion of the study protocol.
• Diabetes
• Use of medication that might have influence on endpoints (e.g. cholesterol lowering medication, hypertension medication)
• Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study in the 180 days prior to the study
• Use of antibiotics in the 30 days prior to the start of the study
• Use of antioxidants, minerals and vitamin supplements available in pharmacies, drugstores, food markets or in alternative medicine
• Pregnancy, lactation
• Abuse of products (> 20 alcoholic consumptions per week and drugs)
• Smoking
• Weight gain or loss (> 3 kg in previous 3 months)
• High physical activity (>4.5 hours of running/week)
• History of any side effects towards intake of olives