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In pediatric age groups communication difficulties very sometimes may present further obstacles in obtaining a detailed injury history and early identification of TBI symptoms.
Most emergency management protocols are focused exclusively on the identification of the relatively small number of patients who may require operative intervention, as early surgery is believed to improve outcome.
However early rehabilitation can also be effective for the much larger number of patients who do not require surgery[1] In addition, Hall and others recently reported that low doses of ionizing radiation to the brain in infancy may influence cognitive abilities in adulthood. [2] Accordingly, increased serum concentrations of, for example S100B ( a calcium-binding protein present in high concentrations in glial cells) and neurone-specific enolase ( NSE: a cytoplasmatic enzyme occuring predominantly in neurones ) have been demonstrated to reflect the presence and severity of brain tissue damage in acute head injuries. [3] In both pediatric age and adults.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Following S100B and NSE in head trauma | Other | Following S100B and NSE in head trauma in correlation with Head CT and post concussion syndrome and Lisat11 |
|
| Measure | Description | Time Frame |
|---|---|---|
| Role of concentration of biomarkers S100B and NSE in serum in mild and moderate head trauma injury in acute phase in relation to head CT and post concusion syndrome. | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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2 groups pediatric and adult.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fatos Kelmendi | Contact | +377 44 128 255 | dr.kelmendifatos@gmail.com | |
| Agon Mekaj, PhD | Contact | +377 44 373545 | dragonmekaj@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fatos Kelmendi | Recruiting | Tirana | Kosovo Prishtina | 10 000 | Albania |
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Biomarkers S100B and NSE in blood sample ( Venous blood)