Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax

Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax

The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.

Inclusion Criteria:

• Subjects in Singapore must be 21 years of age or older and subjects in Korea must be upon completion of 19 years of age or older due to local regulations;
• Able to comprehend and sign an informed consent form;
• Willing and able to complete all postoperative visits;
• Myopia requiring (a) refractive error correction of -0.5 to -8.0 D optical infinity adjusted manifest refraction sphere with (b) astigmatism correction of -0.75 to -5.0 D manifest refraction cylinder and (c) at least 0.75 D of corneal astigmatism.
• Intended treatment targeted for emmetropia;
• Preoperative best-corrected visual acuity (BCVA) of 0 logMAR or better;
• Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

• Pregnant or lactating, current or planned, during the course of the study;
• Dry eye;
• Corneal disease;
• Diagnosis of advanced glaucoma;
• Uncontrolled diabetes;
• Other protocol-defined exclusion criteria may apply.