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A prior study in a tightly controlled clinical research environment found individuals with an alcohol use disorder (AUD) benefited more from inpatient (IP) than outpatient (OP) care, if they presented with high alcohol involvement and/or low cognitive functioning. This study sought to: (a) validate and extend these findings within the uncontrolled environment of a community-based treatment center, and (b) test whether inpatients had fewer days of involuntary abstinence (e.g., incarcerations) relative to outpatients. Based on their need for inpatient treatment, using prior cut-points for alcohol involvement and cognitive functioning, participants were randomly assigned within inpatient need group (No Need for IP; Needs IP) to either 21-days of inpatient substance misuse treatment or 21-days of outpatient treatment, all followed by 6 months of continuing outpatient care. Follow-up were conducted an 90-day intervals across 18 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Inpatient Care + Needs Inpatient | Active Comparator | Individuals with high alcohol involvement or low cognitive functioning receiving inpatient treatment |
|
| Inpatient Care + No Need for Inpatient | Active Comparator | Individuals with low alcohol involvement or mid-high cognitive functioning receiving inpatient treatment |
|
| Outpatient Care + Needs Inpatient | Active Comparator | Individuals with high alcohol involvement or low cognitive functioning receiving outpatient treatment |
|
| Outpatient Care + No Need for Inpatient | Active Comparator | Individuals with low alcohol involvement and or mid-high cognitive functioning receiving outpatient treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Inpatient Care | Behavioral | 21 days of inpatient substance misuse treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Monthly Percentage of Voluntary Abstinent Days (from Timeline Followback Interview) | Percentage of Days Abstinent of those in which drinking was not restricted | Change up to 18 months |
| Monthly Point Prevalence of Abstinent Days (from Timeline Followback Interview) | Monthly percentage of participants abstinent throughout a month | Change up to 18 months |
| Monthly Drinks per Drinking Day (from Timeline Followback Interview) | For those drinking in a month, average drinks per drinking day | Change up to 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| Monthly percentage of Involuntary abstinent days (from Timeline Followback Interview) | Monthly percentage of days in which the participant was incarcerated, hospitalized, or in residential treatment | Up to 18 months |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28150955 | Derived | Rychtarik RG, McGillicuddy NB, Papandonatos GD, Whitney RB, Connors GJ. Randomized clinical trial of matching client alcohol use disorder severity and level of cognitive functioning to treatment setting: A partial replication and extension. Psychol Addict Behav. 2017 Aug;31(5):513-523. doi: 10.1037/adb0000253. Epub 2017 Feb 2. |
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| ID | Term |
|---|---|
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D006760 | Hospitalization |
| D000553 | Ambulatory Care |
| ID | Term |
|---|---|
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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| Outpatient Care | Behavioral | 21 days of outpatient substance misuse treatment |
|