Autologous Platelet Rich Plasma on Low Back Pain

Autologous Platelet Rich Plasma in Ultrasound Guided Intervertebral Disk Injection Therapy for Chronic Low Back Pain

The purpose of this study is to evaluate the effectiveness of autologous platelet-rich plasma (PRP) injection therapy for low back pain patients. Our hypothesis is that PRP will reduce the pain feeling and benefit for restore of the intervertebral disk.

Inclusion Criteria:

• Chronic low back pain more than 2months
• Visual analog scale score more than 4
• Positive X-ray, MRI or CT scan findings
• Pfirrmann grading I-III
• Well understanding and communication ability

Exclusion Criteria:

• History of allergy
• Hemorrhagic trend or use of anticoagulant therapy
• Mental diseases
• Active infection or recent infectious diseases within 3 months
• Local skin infection near the puncture location
• Severe lumbar spinal stenosis, lumbar spondylolisthesis, ossification of posterior longitudinal
• Ligament and lumbar disc herniation（more than 5mm）
• Immunologic diseases
• Tumors
• Metastatic disease
• Recent surgery less than 3 months)
• Pregnancy