Imaging Multiparametric/Multimodality for Lungcancer

Imaging Multiparametric/Multimodality (Magnetic Resonance Imaging Combined With Positron Emission Tomography) for Lungcancer

1. To build an imaging biobank of 200 patients with lungcancer, including pathologic and molecular characteristics of the tumor (mutational status, circulating DeoxyriboNucleic Acid (DNA) from serum biobank…), staging of the cancer (according to the new 2016 Tumor Node Metastasis (TNM) status, the table that classify non-small cell lungcancer) and follow-up informations (Response to first-line treatment (Response Evaluation Criteria in Solid Tumors (RECIST)), disease-free survival, 1-3 years survival).
2. To propose a simple severity scoring system based on tumor features such as size, doubling time (if available), location, amount of enhancement and necrosis. Such approach has been proposed for glioma evaluation (Visually Accessible Rembrandt Images (VASARI)) but is not available for the lung. The objective is to do better than the Tumor Node Metastasis (TNM) staging.
3. To develop and evaluate an IntraVoxel Incoherent Motion (IVIM) protocol for lungcancer evaluation.

Inclusion Criteria:

• Adults over 18 years
• High suspicion of lungcancer confirmed
• Tumor > 2 cm
• Incomplete cerebral staging or not yet realized in the initial consultation of screening

Exclusion Criteria:

• Lungcancer medical history
• During Pregnancy
• Contraindications to MRI
• Patient not able to understand the information of the protocol, taking into account the state of the brain
• Patient unable to keep lying in MRI the necessary time