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| ID | Type | Description | Link |
|---|---|---|---|
| UF 9676 | Other Identifier | Montpellier University Hospital |
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Recommendations for vitamin D supplementation for subjets between 2 and 18 years offer strong sequential doses of vitamin D: 2 times 100 000 units in spaced winter period of 3 months. Data from the literature show a further increase in the incidence of oxalo-calcium stones in children and adolescents associated with hypercalciuria with training Randall plates, essential step lithogenesis calcium oxalate. Knowing the links between vitamin D and urinary calcium excretion, these data lead to the question of increased sensitivity in some children with vitamin D, sensitivity could explain these situations with hypercalciuria increase the gallstone risk. This increased sensitivity to vitamin D may unmask particularly if inputs of high doses of vitamin responsible then a transient hypercalciuria with development of microcrystals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cholecalciferol sequential dose | Experimental | cholecalciferol : 100 000 Unit International (UI), sequential dose (2 mL) |
|
| Cholecalciferol daily dose | Experimental | cholecalciferol : 1000 UI, daily dose during 28 days (0.1 ml by day) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cholecalciferol sequential dose | Drug | sequential dose administration of the treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes from calcium level in urines at day 7, day 14 and day 28 | day 7, day 14 and day 28 |
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Inclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Denis MORIN, MD | Contact | 0467336607 | d-morin@chu-montpellier.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pediatric department | Recruiting | Montpellier | 34295 | France |
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| Cholecalciferol daily dose | Drug | daily dose administration of the treatment |
|
|
| Pediatric department | Recruiting | Nîmes | 30029 | France |
|
| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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