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Laminectomy with PLIF has been shown to achieve satisfactory clinical outcomes, but it leads to potential adverse consequences associated with extensive disruption of posterior bony and soft-tissue structures. The investigators plan to compare the clinical and radiographic outcomes of bilateral decompression with transforaminal lumbar interbody fusion and laminectomy with posterior lumbar interbody fusion in the treatment of degenerative spondylolisthesis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bilateral decompression with TLIF | Experimental | Patients undergoing bilateral decompression with TLIF |
|
| laminectomy with PLIF | Active Comparator | Patients undergoing laminectomy with PLIF |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bilateral decompression with TLIF | Procedure | Bilateral decompression of neural elements combined with TLIF |
|
| Measure | Description | Time Frame |
|---|---|---|
| visual analog scale for low back pain and leg pain | 2 years postoperatively | |
| Oswestry disability index | 2 years postoperatively | |
| Zurich claudication questionnaire | 2 years postoperatively | |
| SF-36 score | 2 years postoperatively | |
| Fusion rate | 2 years postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Surgery procedure duration | Intraoperation | |
| Estimated blood loss | Intraoperation | |
| Length of postoperative hospital stay |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiaofei Cheng, MD | Contact | 8613917556604 | chengxf2015@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Orthopedic Surgery, Shanghai Ninth People's Hospital | Recruiting | Shanghai | 200011 | China |
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| laminectomy with PLIF | Procedure | Decompression of neural elements using laminectomy combined with PLIF |
|
| Pedicle screw and interbody cage | Device | Pedicle screw and interbody cage |
|
| 1 week after hospital discharge |
| Complication | 2 years postoperatively |
| Degree of spondylolisthesis measured by X ray | 2 years postoperatively |
| Disc space height measured by X ray | 2 years postoperatively |
| Lumbar lordosis measured by X ray | 2 years postoperatively |
| ID | Term |
|---|---|
| D013168 | Spondylolisthesis |
| ID | Term |
|---|---|
| D013169 | Spondylolysis |
| D055009 | Spondylosis |
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D007796 | Laminectomy |
| D001052 | Apoferritins |
| D065289 | Pedicle Screws |
| ID | Term |
|---|---|
| D019637 | Orthopedic Procedures |
| D013812 | Therapeutics |
| D019299 | Decompression, Surgical |
| D013514 | Surgical Procedures, Operative |
| D019635 | Neurosurgical Procedures |
| D001059 | Apoproteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D005293 | Ferritins |
| D033862 | Iron-Binding Proteins |
| D002352 | Carrier Proteins |
| D008667 | Metalloproteins |
| D001863 | Bone Screws |
| D016268 | Internal Fixators |
| D019736 | Prostheses and Implants |
| D004864 | Equipment and Supplies |
| D009984 | Orthopedic Fixation Devices |
| D009983 | Orthopedic Equipment |
| D013523 | Surgical Equipment |
| D053831 | Surgical Fixation Devices |
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