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The objective of this study is to use of STIC technology to assist the traditional echocardiography to diagnose the fetal congenital heart disease accurately and then to provide a basis for prenatal counseling.
This is a diagnostic test in Shanghai Xinhua hospital from Nov.2016 to Dec.2017. 265 Cases are gravidas with fetal congenital heart disease diagnosed by echocardiography.Only gravidas who are willing to have complete pregnancy checks and finally delivery or abortion in the hospital are interviewed are eligible for the study. Study participants will be asked for their informed consent.We collect their fetal 2D echocardiography and STIC images every 4-6 weeks during pregnancy and 1 weeks after the baby giving birth we finish their neonatal echocardiography.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fetal congenital heart disease cases | Gravidas with fetal congenital heart disease diagnosed by fetal echocardiography |
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| Measure | Description | Time Frame |
|---|---|---|
| Fetal Congenital heart disease | If an enrolled gravida chooses to terminate her pregnancy, autopsy confirmation will be performed ;If the gravida continues her pregnancy, the outcome will be measured by neonatal echocardiography or surgery. | Nov 2016 to Dec 2018 |
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Inclusion Criteria:
Exclusion Criteria:
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Gravidas with singleton pregnancy living in SHANGHAI
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chen Sun, MD | Contact | 8621-25078485 | chengsun@hotmail.com | |
| Sun Kun, MD | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Xinhua Hospital Shanghai Jiao Tong University School of Medicine | Investigator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xinhua Hospital,Shanghai Jiao Tong University School of Medicine | Recruiting | Yangpu | Shanghai Municipality | 200092 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17556383 | Result | Wren C, Reinhardt Z, Khawaja K. Twenty-year trends in diagnosis of life-threatening neonatal cardiovascular malformations. Arch Dis Child Fetal Neonatal Ed. 2008 Jan;93(1):F33-5. doi: 10.1136/adc.2007.119032. Epub 2007 Jun 7. | |
| 16807954 | Result | Kim N, Friedberg MK, Silverman NH. Diagnosis and prognosis of fetuses with double outlet right ventricle. Prenat Diagn. 2006 Aug;26(8):740-5. doi: 10.1002/pd.1500. |
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| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| ID | Term |
|---|---|
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
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| 14528474 | Result | DeVore GR, Falkensammer P, Sklansky MS, Platt LD. Spatio-temporal image correlation (STIC): new technology for evaluation of the fetal heart. Ultrasound Obstet Gynecol. 2003 Oct;22(4):380-7. doi: 10.1002/uog.217. |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |