Inclusion Criteria:
MRI exam inclusion criteria
- Male volunteer aged in the range 18 to 35 years.
- Acceptance of the research protocol: signature of the informed consent form after oral and written information about the protocol through the patient information document.
- Volunteers that could undergo 1h15 to 1h30 immobilization (MRI exam duration in time).
PET/MRI exam inclusion criteria
- Male volunteer aged in the range 18 to 35 years.
- Acceptance of the research protocol: signature of the informed consent form after oral and written information about the protocol through the patient information document.
- Volunteers that could undergo 1.5 to 2.0 hours immobilization (PET/MRI exam duration in time).
- Volunteers should practice regular physical activity, defined as 50 min per day (in a single session), 2 days per week of physical activity as a minimum (no maximum is fixed).
Exclusion criteria MRI exam exclusion criteria
- Pre-existing neurological or muscular lesions on the legs.
- Co morbidities impeding on the protocol comprehension or fulfilment.
- Illnesses that do not allow to lay down on an examination table.
- Pacemaker holder.
- Metal implants that would preclude MRI imaging
- Claustrophobia: Subjects will be questioned about possible discomfort with being in an enclosed space (e.g., MRI scanner). Those who report such problems will be excluded.
PET/MRI exam exclusion criteria
- Medical radiation exposure within the last five years (normal population should not be exposed to medical radiation higher or equal to 1 mSv per year).
- Pre-existing neurological or muscular lesions on the legs.
- Co morbidities impeding on the protocol comprehension or fulfilment.
- Illnesses that do not allow to lay down on an examination table.
- Pacemaker holder.
- Metal implants that would preclude MRI imaging
- Claustrophobia: Subjects will be questioned about possible discomfort with being in an enclosed space (e.g., MRI scanner). Those who report such problems will be excluded.