Clinical Professor of Shanghai Tongji Hospital
Clinical Professor of Shanghai Tongji Hospital
To establish a genotyping and extraction technology of non invasive prenatal diagnosis for fetal blood group genotype from cell-free fetal DNA in peripheral blood of pregnant women.
To achieve prenatal accurate identification of fetal blood group genotypes，and provide credible theoretical evidence for the prenatal diagnosis and treatment of hemolytic disease of newborn (HDN).
Establish a Non-invasive Prenatal Genotyping and Extraction Technology to Diagnose and Treat the HDN.
Inclusion Criteria:
blood samples of pregnant couples,gender/nation/region is unlimited.
Exclusion Criteria:
adipose or hemolytic samples,overdue samples,unidentified samples