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. The aim of this study, thus, is to evaluate shunt fraction and markers of alveolar distress during one lung ventilation (OLV) at different levels of positive end expiratory pressure (PEEP). Moreover, investigators will focus on predicting factors of high shunt levels during OLV.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low shunt group | patients with shunt less than 30% in one-lung ventilation at ZEEP | ||
| High shunt group | Patients with shunt equal or more than 30% in one-lung ventilation at ZEEP |
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| Measure | Description | Time Frame |
|---|---|---|
| Pulmonary shunt evaluated with ALPE system | every 30 minutes after the start of surgery up to 3 evaluations, up to 90 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| predictors of high intraoperative shunt | All patients admitted to the study received a preoperative physiologic assessment with a cardiovascular evaluation and spirometry. After 15 minutes of one lung ventilation, the pulmonary shunt is evaluated. Therefore, all clinical variable evaluated during preoperative assessment will be compared with the pulmonary shunt | The outcome is assessed 15 minutes after one lung ventilation |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing thoracoscopic surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Azienda Ospedaliero Universitaria Sant'Anna | Ferrara | 44121 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 11575407 | Background | Beck DH, Doepfmer UR, Sinemus C, Bloch A, Schenk MR, Kox WJ. Effects of sevoflurane and propofol on pulmonary shunt fraction during one-lung ventilation for thoracic surgery. Br J Anaesth. 2001 Jan;86(1):38-43. doi: 10.1093/bja/86.1.38. |
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| ID | Term |
|---|---|
| D013896 | Thoracic Diseases |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
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