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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
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The investigators hypothesize that this serious game (designed to provide a learning environment that maximizes opportunities for adolescents with autism to discover the functional utility of eye gaze) will improve sensitivity to eye gaze cues, specifically to identify gazed-at objects, and will also lead to increased social attention to faces in adolescents with autism. The investigators will test this hypothesis in a small-scale exploratory randomized control trial that will include both behavioral and eye tracking outcome measures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Computer Game | Experimental | All Computer Game participants will complete:
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| Waitlist control | No Intervention | All Treatment as usual control participants will complete:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computer Game | Behavioral | The game involves viewing subtle nonverbal behaviors of game characters for the purpose of executing their own goal-directed behavior in the game related to solving various crimes. The learning involves interpreting nonverbal cues on the animated characters, such as pointing, head turns, eye gaze cues. |
| Measure | Description | Time Frame |
|---|---|---|
| Static Eye Gaze Following Task | Eye tracking and accuracy | 2 months |
| Dynamic Eye Gaze Following Task | Eye tracking and accuracy | 2 Months |
| Social/Visual Attention Task | Eye tracking | 2 Months |
| Measure | Description | Time Frame |
|---|---|---|
| Social Responsiveness Scale | Parents completing measure of autism-like behavior in adolescents | 2 months |
| Social Skills Inventory System - Child version | Adolescents completing measure of social skills and problem behaviors in themselves |
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Inclusion criteria:
Exclusion Criteria
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| Name | Affiliation | Role |
|---|---|---|
| Suzy Scherf, PhD | Penn State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pennsylvania State University | University Park | Pennsylvania | 16802 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38182792 | Derived | Scherf KS, Griffin JW, Geier CF, Smyth JM. Social visual attention as a treatment outcome: evaluating the social games for autistic adolescents (SAGA) intervention. Sci Rep. 2024 Jan 5;14(1):619. doi: 10.1038/s41598-024-51332-z. | |
| 30287612 | Derived | Scherf KS, Griffin JW, Judy B, Whyte EM, Geier CF, Elbich D, Smyth JM. Improving sensitivity to eye gaze cues in autism using serious game technology: study protocol for a phase I randomised controlled trial. BMJ Open. 2018 Oct 4;8(9):e023682. doi: 10.1136/bmjopen-2018-023682. |
| Label | URL |
|---|---|
| Improving sensitivity to eye gaze cues in autism using serious game technology: study protocol for a phase I randomised controlled trial | View source |
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The data will be shared in the NIMH National Data Archive
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| ID | Term |
|---|---|
| D001321 | Autistic Disorder |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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Participants randomized into intervention or standard care control conditions
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Given the design of the study, parents and adolescents will know the condition to which they have been assigned. However, researchers involved in data collection will be blinded from condition assignment during the pre-intervention data collection session as these data will be collected prior to randomization. Also, the research team is not involved in the randomization process. The research team members who are involved in ensuring the fidelity of the intervention are not involved in data collection procedures. Although we will attempt to limit unblinding, it is not possible for researchers involved in data collection to be completely blinded to the assignment of participant condition at the post-intervention visit as we cannot prohibit participants from talking to researchers about their experience in the study. Importantly, the primary outcome measures are believed to be robust to investigator bias.
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| 2 months |
| Social Skills Inventory System - Adult version | Parents completing measure of social skills and problem behaviors in adolescents | 2 months |
| Treatment as Usual | Parents reporting on social and behavioral treatments adolescents receiving in and out of school | 2 months |