Retrospective study to evaluate if FIBTEM predicts the amount of postoperative bleeding in total knee replacement patients.

This retrospective study evaluate patients who underwent total knee replacement arthroplasty. Laboratory coagulation parameters, including FIBTEM, before anesthesia induction and after admission to the post-anesthetic care unit and decrement of postoperative haemoglobin and amount of transfusion were reviewed.

A correlation coefficient of ρ = 0.4 was calculated from a pilot study. We need at least 44 subjects with an α value of 0.05 and a power of 0.8.

Inclusion Criteria:

• patients who underwent primany unilateral total knee replacement arthroplasty under general anesthesia
• patients who had FIBTEM performed

Exclusion Criteria:

• surgery under regional anaesthesia
• a simultaneous bilateral total knee replacement arthroplasty
• the second surgery of staged total knee replacement arthroplasty
• revision of total knee replacement arthroplasty
• patients who received intraoperative transfusion
• patients who use tranexamic acid
• patients who received fibrinolytic agents because of perioperative thromboembolic event
• patients who refused transfusion because of religious belief of personal causes

total knee replacement patients