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| Name | Class |
|---|---|
| University of Adelaide | OTHER |
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OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.
OBJECTIVE: Current practice requires histopathological assessment to confirm diagnosis for colorectal lesions detected at colonoscopy. Advances in endoscopic imaging contribute for real-time diagnosis which, apart from being cost and time-saving, also guides decision-making and reduces risks. Our study aimed to compare a recently-developed endoscopic classification with an established one.
DESIGN: The modified Sano's classification (MS) was compared to the Narrow Band Imaging (NBI) International Colorectal Endoscopic classification (NICE) in a randomised trial between 2013 and 2015. An experimented endoscopist classified each polyp, what was compared to histopathology.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Modified Sano's Classification | Experimental | Modified Sano's Classification as described by Singh et al. 2013 |
|
| NICE classification | Active Comparator | NBI International Colorectal Endoscopic Classification as described by Hewett et al. 2012 |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Modified Sano's classification | Other | Set of characteristics described by Singh et al. 2013 to evaluate colorectal lesions. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy measures in comparison to the final histopathology in regards to polyps' subtype (neoplastic versus non-neoplastic) | Comparison of NICE or MS with the final histopathology in regards to polyps' subtype (i.e. non-neoplastic = Hyperplastic Polyp (HP) and neoplastic = Sessile Serrated Adenoma/Polyp (SSA/P), Adenomatous Polyp (AP), Traditional Serrated Adenoma (TSA), superficial cancer and invasive cancer) | After two weeks of the colonoscopy |
| Accuracy measures in comparison to the final histopathology in regards to polyps' invasiveness | Comparison of NICE or MS with the final histopathology in regards to invasiveness (SSA/P, AP, TSA or superficial cancer versus invasive cancer) | After two weeks of the colonoscopy |
| Accuracy measures in comparison to the final histopathology in regards to polyps' subtype (SSA/P versus non-SSA/P) | Comparison of MS with the final histopathology in regards to SSA/P (SSA/P versus non-SSA/P) | After two weeks of the colonoscopy |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy in regards to negative predictive value of diminutive distal colorectal polyps | Comparison of NICE or MS with the final histopathology in regards to <5 mm distal to the sigmoid polyps (NPV for HPs - according to the PIVI guidelines) | After two weeks of the colonoscopy |
| Agreement in predicting post-colonoscopy surveillance interval with final histopathology |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Leonardo ZC Pu, MD, MSc | The Lyell McEwin and The University of Adelaide | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23617643 | Background | Singh R, Jayanna M, Navadgi S, Ruszkiewicz A, Saito Y, Uedo N. Narrow-band imaging with dual focus magnification in differentiating colorectal neoplasia. Dig Endosc. 2013 May;25 Suppl 2:16-20. doi: 10.1111/den.12075. | |
| 22609383 | Background | Hewett DG, Kaltenbach T, Sano Y, Tanaka S, Saunders BP, Ponchon T, Soetikno R, Rex DK. Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow-band imaging. Gastroenterology. 2012 Sep;143(3):599-607.e1. doi: 10.1053/j.gastro.2012.05.006. Epub 2012 May 15. |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| NICE classification | Other | Set of characteristics described by Hewett et al. 2012 to evaluate colorectal lesions. |
|
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Comparison of NICE or MS with the final histopathology in regards to prediction of surveillance interval (according to the PIVI guidelines) |
| Immediately after the colonoscopy (endoscopic) and 2 weeks after (histopathology) |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |