Effect of Standard Normothermia Protocol On Surgical Site Infections

Effect of Standard Normothermia Protocol On Surgical Site Infections: Randomized Controlled Trial

Aim of this study is to investigate the efficiency of a standard normothermia protocol and effects on postoperative Surgical Site Infection (SSI) rate.

Inclusion Criteria:

• Elective
• Preoperatively not infected/dirty Surgical Site
• Open major abdominal operations (hepatobiliary, upper gastrointestinal or colorectal); under general anesthesia, longer than 30 minutes)

Exclusion Criteria:

• Emergent surgery
• Local/locoregional procedures
• Laparoscopic operation
• Minor abdominal operations (e.g. hernia repair, colostomy closure)
• Malign hyperthermia
• Signs of active infection or fever
• Immunosuppression
• Severe malnutrition
• Kidney/liver failure and antibiotic use within the previous 1 week or immunosuppressive use (chemotherapy, steroids.) within the previous 1 month and reversal of patients opinion while randomization period