Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| U1111-1131-7209 | Other Identifier | WHO |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This trial is conducted in The United States of America. The aim of this trial is to investigate Safety, Tolerability, Pharmacokinetics (the exposure of the trial drug in the body) and Pharmacodynamics (the effect of the investigated drug on the body) of Multiple Dosing of NNC0174-0833 in Subjects with Obesity or Overweight.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NNC0174-0833 | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| NNC0174-0833 | Drug | Doses of NNC0174-0833, dosed either once daily or once weekly |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Number of treatment emergent adverse events (TEAEs) | From time of first dosing (Day 1) to the post-treatment follow-up visit (Day 99) |
| Measure | Description | Time Frame |
|---|---|---|
| The area under the NNC0174-0833 plasma concentration-time curve | [only applicable for once daily dosing] | From time 0 to 24 hours at steady state |
| The area under the NNC0174-0833 plasma concentration-time curve |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Global Clinical Registry (GCR, 1452) | Novo Nordisk A/S | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Novo Nordisk Investigational Site | Overland Park | Kansas | 66212 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo |
| Drug |
Dosed either once daily or once weekly |
|
[only applicable for once weekly dosing]
| From time 0 to 168 hours at steady state |
| The maximum concentration of NNC0174-0833 in plasma at steady state | Day 1; Day 57 |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided