The purpose of this study is to determine the kinetics of 13C-eicosapentaenoic acid (EPA) and 13C-arachidonic acid (AA) in young and older participants

Inclusion Criteria:

• six young (18-30 y old) and six older (≥ 70 y old)
• healthy non medicated participants.

Exclusion Criteria:

• Tobacco,
• malnutrition (assessed from blood albumin, haemoglobin and lipids), -
• participants taking an EPA+DHA supplements or consuming more than 2 fish meals per week,
• severe gastro-intestinal problems,
• medication for diabetes,
• thyroid disease,
• renal failure,
• cancer,
• psychiatric difficulties or depression,
• cardiovascular disease,
• glucose intolerance (>8 mmol/L in fasted samples)
• chronic immune condition or inflammation (CRP > 10 mg/l, white cell count),
• recent major surgery or cardiac event,
• dementia,
• ongoing or past severe drug or alcohol abuse,
• ongoing or past intensive physical training.

Young and elderly healthy participants