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| ID | Type | Description | Link |
|---|---|---|---|
| Y6D1846194a | Registry Identifier | CNIL | |
| 16-532bis | Other Identifier | CCTIRS |
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Due to lack of funding
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Iodinated contrast media are now frequently used in diagnostic imaging exams, including pediatrics.
In adults, the acute renal failure (ARF) associated with contrast agents (CA-AKI) occur in 3-33% of exposed patients, especially as the patient is fragile, has comorbidities or pre-existing renal aggression .
In children, the prevalence of this little known disease is probably underestimated.
The investigators intend to conduct a prospective epidemiological study, to estimate the impact of the acute renale failure to iodinated contrast agents in pediatrics.
Patients will be included those of pediatric emergencies, Hospitalization Unit of Short Duration pediatric, pediatric intensive care and pediatric resuscitation. The acute renale failure will be estimated on the basis of criteria KDIGO (score of kidney disease) group in 2012 to 48 hours a computed tomography (CT) scan with injection of contrast media, based on a change in creatinine clearance of the estimated according to the formula Schwartz revised in 2009 and / or diuresis.
Patient characteristics will be identified in order to establish risk factors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CT scan with iodinated contrast agents | Patients under 16 years old and must pass a CT scan with iodinated contrast agents. The following data will be collected in the medical record (creatinine prior to injection, comorbidities and child characteristics, associated treatments and risk factors of acute renal failure, as well as the injection pattern). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CT scan with iodinated contrast agents | Other | Before the CT scan, the investigators with iodinated contrast agents, the following data will be collected in the medical record: creatinine prior to injection, comorbidities and child characteristics, associated treatments and risk factors of acute renal failure, as well as the injection pattern. After the CT scan the investigators will collect the characteristics of the injection type, osmolarity and volume of contrast used and the appearance of a possible allergic reaction. Then 24 and 48 hours and day 7 will collect serum creatinine, urine output and vital replacement therapies may be necessary. |
| Measure | Description | Time Frame |
|---|---|---|
| Creatinine | data gathered in the medical file | change from baseline creatinine at 7 days |
| Diuresis | data gathered in the medical file | change from baseline diuresis at 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Readmission | Number of patients with no or having an adverse event during the readmission. | at 7 days |
| Hospitalization in intensive care | Number of patients with no or having an adverse event during the hospitalization in intensive care. |
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Inclusion Criteria:
Exclusion Criteria:
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patients less than 16 years and who enjoys receiving an injected CT.
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| Name | Affiliation | Role |
|---|---|---|
| Olivier MORY, MD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Lyon | Lyon | 69310 | France | |||
| Chu Saint-Etienne |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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|
| at 7 days |
| Renal replacement | Number of patients with no or having an adverse event during the renal replacement. | at 7 days |
| Death | Number of dead | at 7 days |
| Saint-Etienne |
| 42055 |
| France |
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |