Efficacy and Necessity of Anti-inflammatory Drops After Laser Peripheral Iridotomy

Efficacy and Necessity of Anti-inflammatory Drops After Laser Peripheral Iridotomy

The purpose of this study is to evaluate the efficacy and need for prescribing anti-inflammatory topical drops to patients undergoing laser peripheral iridotomy.

Primary closed angle glaucoma is responsible to almost half glaucoma related blindness around the world. Laser peripheral iridotomy (LPI) is a common and simple treatment used for both treatment and prevention of acute angle closure event.

Anti-inflammatory drops are commonly prescribed to patients undergoing LPI in order to prevent or reduce post-treatment discomfort. However, to date, there are no specific guidelines for post LPI anti-inflammatory treatment, nor sufficient clinical evidence regarding the efficacy of such treatment.

In the current study, the investigators aim to evaluate the effect of topical steroids and non-steroidal anti-inflammatory drugs (NSAIDs) on post LPI symptoms and inflammation markers.

Inclusion Criteria:

• Diagnosis of primary narrow/closed angle by gonioscopy
• Able to give consent
• Ability to attend follow-up visits

Exclusion Criteria:

• Corneal disease preventing sufficient evaluation of the angle
• Secondary closed angle (e.g. uveitis related)
• Pregnant women
• Previous eye surgery other than laser refractive correction