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Loss of interest in the subject
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Tracheal resection and reconstruction (TRR) is the treatment of choice for most patients with tracheal stenosis or tracheal tumors .The postintubation tracheal stenosis is the common indication for (TRR).The immediate postoperative period can be anxiety provoking for some reasons such as requirement to maintain a flexed neck, oxygen mask, and surgical pain which inadequately treated.
Bilateral superficial cervical plexus block (BSCPB) is a popular regional anesthesia technique for its feasibility and efficacy. The use of regional anesthesia in combination with general anesthesia may lighten the level of general anesthesia required , provide prolonged postoperative analgesia and reduce the requirements for opioid analgesics
Local anesthetic infiltration into the surgical incision can relieve pain at the wound site after surgery, as part of multimodal analgesic approach.
Levobupivacaine, is "S"-enantiomer of bupivacaine, has strongly emerged as a safer alternative for regional anesthesia than bupivacaine . Levobupivacaine has been found to be equally efficacious as bupivacaine, but with a superior pharmacokinetic profile. Clinically, levobupivacaine has been observed to be well tolerated in regional anesthesia techniques both after bolus administration and continuous post-operative infusion.
The aim of this study is to evaluate the intra- and postoperative efficacy of local wound infiltration versus bilateral superficial cervical plexus block with levobupivacaine for upper tracheal resection and reconstruction surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Superficial cervical plexus block | Experimental | Patients will receive bilateral superficial cervical plexus block using levobupivacaine |
|
| Local wound infiltration | Active Comparator | Patients will receive local wound infiltration with levobupivacaine after the conclusion of surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Superficial cervical plexus block | Procedure | Patients will receive bilateral superficial cervical plexus block |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative pain score | Postoperative pain scores will be assessed using postoperative visual analogue score | For 24 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Systolic blood pressure | For 4 hours after start of surgery | |
| Diastolic blood pressure | For 4 hours after start of surgery | |
| Heart rate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hanaa M Elbendary, MD | Department of Anaesthesia, Surgical Intensive Care and Pain Medicine, College of Medicine, Mansoura University, Mansoura, Egypt | Study Chair |
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| Local wound infiltration | Procedure | Patients will receive local wound infiltration |
|
| For 4 hours after start of surgery |
| Peripheral oxygen saturation | For 4 hours after start of surgery |
| End-tidal Carbon dioxide tension | For 4 hours after start of surgery |
| Bispectral index | For 4 hours after start of surgery |
| Duration of analgesia | It is defined as time taken for first analgesic request of analgesia from extubation | For 24 hours after surgery |
| Cumulative analgesic consumption | total analgesics used for 24 hrs after surgery | For 24 hours after surgery |
| Cortisol serum | Plasma cortisol assay | before induction ,one hour after start of surgery and one hour after end of surgery |