Treatment of anal cancer has been always linked to quality of life. Recently, with development on radiotherapy technique, toxicities have been lowered with the maintenance of adequate rates of disease control. This trial intends to follow patients prospectively with questionnaires to evaluate sexual quality of life among patients who are who men who have sex with other men and have been subject to concurrent chemoradiotherapy with IMRT technique.

In this prospective single-arm cohort, patients who are men who have sex with other men will be recruited to answer routine questionnaires on quality of life in general and sexual quality of life in specific, most validated and other waiting for validation in Portuguese language. These questionnaires will be applied after the diagnose and before the beginning of the treatment, on the last day of treatment, and 3, 6 and 12 months after the treatment is completed. Only patients who will be treated with concurrent chemotherapy will be recruited, and intensity-modulated radiotherapy technique is mandatory.

Inclusion Criteria:

• Anal cancer proven biopsy
• men who have sex with other men
• curative intent of treatment
• IMRT required
• concurrent chemotherapy required

Exclusion Criteria:

• Patients who have undergone surgery for anal cancer
• patients who can't read, write or are unable to answer to questionnaire

Patients diagnosed with anal cancer who are men who have sex with other men and are able to answer to questionnaires