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This study aims to establish radiomics database for pancreas cancer from multiparametric MRI including DCE-MRI obtained by using incoherent undersampling and radial acquisition for clinical staging as well as quantitative analysis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| multi-parametric MRI | Procedure | multiparametric MRI is performed in all patients, and the sequence includes dynamic contrast enhanced (DCE) MRI, diffusion weighted imaging (DWI), tissue maps, and MR cholangiography. |
| Measure | Description | Time Frame |
|---|---|---|
| T-staging | T-staging of the tumor at MRI. | 4 weeks after MR acquisition |
| Measure | Description | Time Frame |
|---|---|---|
| N-staging | N-staging of the tumor at MRI | 4 weeks after MR acquisition |
| arterial blood flow | arterial blood flow of the tumor and adjacent parenchma on DCE-MRI |
| Measure | Description | Time Frame |
|---|---|---|
| T1 value | T1 value of the tumor and adjacent parenchyma using T1 map | 4 weeks after MR acquisition |
| T2 value | T1 value of the tumor and adjacent parenchyma using T2 map |
Inclusion Criteria:
Exclusion Criteria:
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Patients who are scheduled to undergo pancreatobiliary MRI as a preoperative workup for suspected resectable pancreas cancer (adenocarcinoma)
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| Name | Affiliation | Role |
|---|---|---|
| Jeong Min Lee, MD | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | South Korea |
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| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
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| 4 weeks after MR acquisition |
| arterial fraction | arterial fraction of the tumor and adjacent parenchyma on DCE-MRI | 4 weeks after MR acquisition |
| mean transit time | mean transit time of the tumor and adjacent parenchyma on DCE-MRI | 4 weeks after MR acquisition |
| extracellular volume | extracellular volume of the tumor and adjacent parenchyma on DCE-MRI | 4 weeks after MR acquisition |
| true diffusion | true diffusion of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model | 4 weeks after MR acquisition |
| pseudodiffusion | pseudodiffusion of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model | 4 weeks after MR acquisition |
| perfusion fraction | perfusion fraction of the tumor and adjacent parenchyma on DWI with intravoxel incoherent motion model | 4 weeks after MR acquisition |
| kurtosis | kurtosis of the tumor and adjacent parenchyma on DWI with kurtosis model | 4 weeks after MR acquisition |
| mean diffusivity | mean diffusivity of the tumor and adjacent parenchyma on DWI with kurtosis model | 4 weeks after MR acquisition |
| 4 weeks after MR acquisition |
| fat fraction | fat fraction of the tumor and adjacent parenchyma using T2* corrected fat map | 4 weeks after MR acquisition |
| global textural feature | first order parameters related to the grey level frequency distribution in the region of interest using dedicated software | 4 weeks after MR acquisition |
| local textural feature | second order parameters calculated with spatial grey level dependence matrices or co-occurrence matrices using dedicated software | 4 weeks after MR acquisition |
| attenuation | hounsefield unit (HU) of the tumor and parameter on CT within 4 weeks of MRI | 4 weeks after MR acquisition |
| transient dyspnea | development of transient dyspnea or involuntary motion after contrast media administration | 1 day after MR acquisition |
| D004066 |
| Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |