Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Facial eczema and perioral dermatitis are clinical entities that develop exclusively in the face and present a special therapeutic challenge. Topical corticosteroids that are commonly applied to treat eczema/dermatitis at other body sites are best avoided in the face, as they may result in rapid atrophy of facial skin and in the long term rather aggravate facial dermatoses. Black tea compresses have been successfully used by German-speaking dermatologists to treat facial eczema/dermatitis for decades. The precise mechanism of action is unknown but is presumably based on astringent properties of tannins in the black tea and on the antiinflammatory action of a wet compress as such. This therapy is cheap, universally available and practically free of side-effects. Despite these perceived advantages the effects and tolerance of black tea compresses have not been formally studied to date. Therefore, the investigators plan to treat 25 patients with facial eczema/perioral dermatitis over a period of 6 days each within the current trial. The disease activity will be assessed before, during and after completion of treatment using several clinical scores. In addition, side-effects, if any, will be documented.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Black tea | Other | Black tea compress treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Black tea compress treatment | Other | Wet compresses with black tea applied 4-5 times daily to the face for 6 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Facial Eczema Activity and Severity Index (patients with facial eczema) | days 0, 3 and 6 | |
| Change in Perioral Dermatitis Severity Score (patients with perioral dermatitis) | days 0, 3 and 6 | |
| Change in Investigator´s Global Assessment Score (all patients) | days 0, 3 and 6 | |
| Change in Patient´s Self-Assessment Score (all patients) | days 0, 3 and 6 | |
| Change in Visual Analog Scale for pruritus in the face (patients with facial eczema) | days 0, 3 and 6 | |
| Change in Visual Analog Scale for tension feeling in the face (patients with perioral dermatitis) | days 0, 3 and 6 |
| Measure | Description | Time Frame |
|---|---|---|
| Side-effects | days 3 and 6 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Iakov Shimanovich, MD | University of Lübeck | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Dermatology, University of Lübeck | Lübeck | Schleswig-Holstein | 23538 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30668184 | Derived | Witte M, Krause L, Zillikens D, Shimanovich I. Black tea dressings - a rapidly effective treatment for facial dermatitis. J Dermatolog Treat. 2019 Dec;30(8):785-789. doi: 10.1080/09546634.2019.1573306. Epub 2019 Feb 3. |
Not provided
Not provided
It is planned to publish the study results, including anonymized clinical patient data and photographs in a scientific journal.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D004485 | Eczema |
| D003872 | Dermatitis |
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D017443 | Skin Diseases, Eczematous |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided