Status Asthmaticus on the Intensive Care Prospective - STATIC PRO

Risk Factors for Intensive Care Admission of Children With Severe Acute Wheeze or Asthma (SAA)

This study will prospectively assess the impact and relevance of several risk factors for children with severe acute asthma (SAA) or acute wheeze that have been identified in retrospective studies. Secondary we will assess short-term medical and psychosocial functioning in patient (and parents) admitted to a PICU for SAA/acute wheeze versus a control group admitted to a MC for SAA/acute wheeze.

Inclusion Criteria:

• Between 2 and 18 years of age
• Admission to a PICU for SAA or acute wheeze or admission to a MC for SAA or acute wheeze

Exclusion Criteria:

• Patient is outside of specified age range
• Down's Syndrome
• Congenital/acquired heart defect that interferes with normal SAA treatment
• Congenital/acquired airway defect (tracheomalacia/bronchomalacia)
• Primary/secondary immunodeficiency
• Pre-existing chronic pulmonary condition, known to mimic asthma: Cystic Fibrosis, Bronchopulmonary dysplasia, Bronchiolitis obliterans
• If both parents are not able to speak the Dutch language