Tranexamic Acid for Preventing Postpartum Hemorrhage After Cesarean Section

It is a multicenter randomized, double-blind and placebo-controlled trial. Totally 6500 women to delivery by cesarean section will be recruited in this study. In addition to routinely oxytocin, the women in study group will receive TXA 1 g in 2 minutes after they delivered their babies, and those in control group will receive placebo. The incidence of postpartum hemorrhage, the amount of bleeding, as well as the side effects will be observed.

Inclusion Criteria:

• gestational week more than 37;
• to delivery by cesarean section;
• informed consent form signed

Exclusion Criteria:

• Any known renal or liver disorders
• History of venous or arterial thrombosis
• Any disease or history tend to increase thrombosis: opertion in 1 month; active smoker.
• Do cesarean section because of active bleeding