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| Name | Class |
|---|---|
| Weizmann Institute of Science | OTHER |
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The purpose of this study is to examine if investigators can improve diagnosis of prostate cancer by using MRI/DTI?
This is a prospective cohort study of the ability of MRI/DTI to diagnose prostate cancer in men undergoing prostate MRI.
Study design: Male adults who are scheduled to undergo MRI of the prostate, for clinical reasons, will be subjected to additional 10 minutes of image acquisition inside the MRI machine. The added MRI/DTI acquisition does not involve injection of additional contrast material. Investigators will compare between ability of the full mp-MRI images to diagnose prostate cancer to that of the MRI/DTI images
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DTI acquisition | Experimental | Addition of up to 10 minutes in MRI machine purpose of acquiring additional DTI images |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI machine | Device | The Philips Ingenia 3.0T is an MRI machine intended to be used by specialist radiologists in the hospital. It is able to acquire high quality images of wide variety of organs. For imaging the prostate, T2-weighted turbo spin-echo images are normally obtained in three orthogonal planes (axial, sagittal and coronal). This device is been clinically used in the MRI department in Belinson hospital. |
| Measure | Description | Time Frame |
|---|---|---|
| Compare between number of prostate cancer diagnosed by mpMRI to the ones diagnosed by MRI/DTI | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Compare the correlation of MRI/DTI parameters with prostate cancer diagnosis to the ones measured by mpMRI (ADC, and diffusion weighted images). | 1 year | |
| Compare between MRI/DTI and MRI ability to identify low-grade and high-grade prostate cancer | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
1) Men who cannot complete the full acquisition of the MRI and the MRI/DTI image sequences for any reason.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rabin Medical Center | Petah Tikva | 4941492 | Israel |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| Compare between MRI/DTI and MRI in their ability to estimate tumor size. | 1 year |
| Compare between MRI/DTI and MRI in PiRAD grading | 1 year |
| D005832 |
| Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |