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Investigators researched the effect of two different types of drugs on core body temperature during magnetic resonance imaging. The hypothesis is in ketamine group, thermo disregulation is not as distinct as in propofol group, due to its positive effect on thermo regulation
Intravenous anesthetics may impair thermoregulation. Absorption of radiofrequency waves by the body surface may result in heating, especially in small children during magnetic resonance imaging (MRI). Investigators applied two different intravenous anesthetics as propofol and ketamine and studied the effect of these drugs on core body temperature.
All patients aged between 6 months-10 years were administered midazolam and atropine. After that 1 mg/ kg of propofol was applied in group I, and 0,1 ml/kg of propofol ketamine mixture ( 10 mg/ml each) was applied in group II. Core body temperatures were taken before and after MRI and compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| propofol | Active Comparator | body core temperature was measured from tympanic membrane after 1 mg/kg propofol administration, before and after magnetic resonance imaging |
|
| ketofol | Active Comparator | body core temperature was measured from tympanic membrane after 0,1 ml/kg administration of ketamine propofol mixture of 10 mg/ml both, before and after magnetic resonance imaging |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| propofol | Drug | propofol, midazolam and atropine administration via intravenous cannula. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in core body temperature | temperature was taken from tympanic membrane bilaterally before and after MRI. If temperature change was more or les than 0.1 degrees celsius the patient was considered as warmer or cooler. | during magnetic resonance imaging (MRI) procedure |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D015742 | Propofol |
| ID | Term |
|---|---|
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
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| Ketamine propofol mixture | Drug | Administration of ketamine propofol mixture, midazolam and atropine via intravenous cannula |
|
|
| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |