Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects

Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects - Molecular Insights Through Integration of Transcriptomics of Peripheral Blood Mononuclear Cells (PBMC) and Circulating miRNA

This study aims to investigate the effect of mixed of herbs and spices on gene expression of pathways associated with glucose homeostasis, oxidative stress, inflammation and its interrelation with circulating miRNA, in the postprandial phase in healthy human subjects.

Inclusion Criteria:

• Healthy males and females
• BMI 23-33 kg/m2
• Must be able to accept spices
• Agreed and signed informed consent

Exclusion Criteria:

• Below 18 years old
• Uncomfortable speaking English and/or difficulties in understanding spoken English
• Smoking or using snuss
• Vegetarian or vegan
• Having food allergies
• Stressed by venous blood sampling or previous experience of being difficult to be cannulated
• Receiving any drug treatment that may influence the study outcomes
• Pregnancy or breastfeeding