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The purpose of this study is to investigate whether a comprehensive group education combined with a lifestyle "activation" program that includes (a) sleep hygiene course, (b) physical activity promotion, and (c) bright light therapy, can improve both sleep quality and cognitive function among 96 community-dwelling older adults.
96 community-dwelling older adults with sleep complaints will be randomized into either a 6-month life style and sleep activation intervention program or a waitlist control group (participants in this group will be offered an abbreviated version of the program upon completion of the 6 month study). There are 3 measurement sessions to measure cognition, sleep, and physical activity at the onset of the study, the midway (3 month) point, and completion (at 6 months).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Life Style and Sleep Group | Experimental | Participants randomized into this group will undergo a 4 week sleep hygiene course (classes 1x/week for 1.5 hours), followed by a 20 week lifestyle activation program. During the 20 week lifestyle activation program, participants wear a Fit Bit and receive a call from a fitness professional every other week for motivation and recommendations, and receive a bright light therapy program from a sleep expert based on their initial sleep results at the baseline measurement session. |
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| Wait-list Control | No Intervention | Participants randomized into this group will complete all measurement sessions. After completion of the final measurement session (6 months), participants will be offered an abbreviated version of the Life Style and Sleep Group intervention including the sleep hygiene course, consultation with sleep expert to go over individual sleep patterns and be given recommendations, along with physical activity recommendations from a fitness expert. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Life Style and Sleep Intervention | Behavioral |
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| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in sleep quality as measured by Motion Watch 8 at 3 and 6 months | Baseline, 3 months, and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in cognitive function as measured by the Alzheimer's Disease Assessment Scale Cognitive Subscale Plus (ADAS-Plus) at 3 and 6 months | Baseline, 3 months, and 6 months | |
| Change from baseline in self-reported sleep quality as measured by the Pittsburgh Sleep Quality Index at 3 and 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Teresa Liu-Ambrose, PhD | University of British Columbia | Principal Investigator |
| Glenn Landry, PhD | University of British Columbia | Principal Investigator |
| Linda Li, PhD | University of British Columbia | Principal Investigator |
| Catherine Chan, MPT | University of British Columbia | Principal Investigator |
| John Best, PhD | University of British Columbia | Principal Investigator |
| Cindy Barha, PhD | University of British Columbia | Principal Investigator |
| Jennifer Davis, PhD | University of British Columbia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of British Columbia | Vancouver | British Columbia | V6T 1Z3 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40693459 | Derived | Balbim GM, Boa Sorte Silva NC, Falck RS, Kramer AF, Voss MW, Liu-Ambrose T. 24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment. Alzheimers Dement. 2025 Jul;21(7):e70496. doi: 10.1002/alz.70496. | |
| 32444553 | Derived | Falck RS, Davis JC, Best JR, Chan PCY, Li LC, Wyrough AB, Bennett KJ, Backhouse D, Liu-Ambrose T. Effect of a Multimodal Lifestyle Intervention on Sleep and Cognitive Function in Older Adults with Probable Mild Cognitive Impairment and Poor Sleep: A Randomized Clinical Trial. J Alzheimers Dis. 2020;76(1):179-193. doi: 10.3233/JAD-200383. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jan 20, 2026 | |
| Reset | Feb 5, 2026 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jan 20, 2026 | Feb 5, 2026 |
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| Baseline, 3 months, and 6 months |
| Change from baseline in physical activity levels as measured by Motion Watch 8 at 3 and 6 months | Baseline, 3 months, and 6 months |
| Change from baseline in self-reported physical activity levels as measured by CHAMPS physical activity questionnaire each month | Monthly, from baseline through 6 months |
| 30119694 | Derived | Falck RS, Davis JC, Best JR, Li LC, Chan PCY, Wyrough AB, Landry GJ, Liu-Ambrose T. Buying time: a proof-of-concept randomized controlled trial to improve sleep quality and cognitive function among older adults with mild cognitive impairment. Trials. 2018 Aug 17;19(1):445. doi: 10.1186/s13063-018-2837-7. |