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Arthritis is a current manifestation of systemic lupus erythematosus (SLE) and participates to the SLEDAI composite score calculation (0 to 105). Ultrasonography (US) is a validated and sensitive tool for joint assessment. Published studies showed US joint abnormalities in systemic lupus erythematosus patients with or without joint pain. Nevertheless, ultrasonography evaluations were not standardized and no study compared clinical and ultrasonography assessments. The objectives were 1) to describe ultrasonography joint abnormalities in systemic lupus erythematosus population, 2) to compare clinical and ultrasonography standardized joint assessments, 3) to estimate the reliability of clinical swollen joint count (C-SJC) and SLEDAI (C-SLEDAI) score versus ultrasonography-SJC and ultrasonography-SLEDAI.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ultrasonography | Experimental | B-mode and power Doppler Ultrasonography examination |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasonography | Other | B-mode and power Doppler ultrasonography examination.Ultrasonography assessments includes wrists, metacarpophalangeal, proximal interphalangeal, elbows, shoulders, knees, ankles, metatarsophalangeal and twenty six tendons (wrist extensors, finger flectors and tendons of the ankles). |
| Measure | Description | Time Frame |
|---|---|---|
| Ultrasonography record (synovitis / tenosynovitis / effusion) | Day 0 (there is only one point measurement in the study) | |
| Clinical joint assessment (synovitis / tenosynovitis / effusion) | Day 0 | |
| Evaluate SELENA SLEDAI (C-SLEDAI) score | Day 0 | |
| Evaluate musculoskeletal BILAG score | Day 0 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Carine SALLIOT | CHR ORLEANS | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital Pellegrin | Bordeaux | 33076 | France | |||
| Chu de Brest |
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| ID | Term |
|---|---|
| D008180 | Lupus Erythematosus, Systemic |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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| ID | Term |
|---|---|
| D019220 | High-Energy Shock Waves |
| ID | Term |
|---|---|
| D000069453 | Ultrasonic Waves |
| D013016 | Sound |
| D011840 | Radiation, Nonionizing |
| D011827 | Radiation |
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|
| Brest |
| 29609 |
| France |
| CH du MANS | Le Mans | 72037 | France |
| CHU Hôtel Dieu | Nantes | 44093 | France |
| CHR d'Orléans | Orléans La Source | 45067 | France |
| Hopital Pontchaillon - Chu de Rennes | Rennes | 35033 | France |
| Chru de Tours | Tours | 37044 | France |
| D055585 |
| Physical Phenomena |