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The objective of the study is to investigate the exposure difference between antibiotic studied patients in intensive care with Extracorporeal Membrane Oxygenation and patients without Extracorporeal Membrane Oxygenation.
The exhibition is evaluated by population pharmacokinetic modeling.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ECMO piperacillin | patients in intensive care treated with ECMO with antiinfective therapy : piperacillin |
| |
| without ECMO piperacillin | patients in intensive care without ECMO with antiinfective therapy : piperacillin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood sample | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measure exposure to piperacillin | evaluated by population pharmacokinetic modeling and is defined by the time during which the antibiotic concentration is greater than 4 times the critical concentration of the germ to treat | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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Patients in intensive care treated with ECMO or without ECMO
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| Name | Affiliation | Role |
|---|---|---|
| Pierre Fillatre | Rennes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Rennes | Rennes | France |
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| ID | Term |
|---|---|
| D007239 | Infections |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |