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Cell-count related risk factors for acute kidney injury after cardiovascular surgery have been reported. The authors attempted to investigate whether the perioperative cell counts of neutrophil, lymphocyte, platelet are associated with the postoperative acute kidney injury and long-term mortality after cardiovascular surgery using cardiopulmonary bypass.
Acute kidney injury (AKI) after cardiovascular surgery remains a serious complication associated with increased mortality for up to 10 years. The incidence of AKI after cardiovascular surgery is as high as 55% and the incidence of renal replacement therapy (RRT) to be up to 8 %.
Cell-count related risk factors for acute kidney injury after cardiovascular surgery have been reported. The authors attempted to investigate whether the perioperative cell counts of neutrophil, lymphocyte, platelet are associated with the postoperative acute kidney injury and long-term mortality after cardiovascular surgery using cardiopulmonary bypass.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cardiovascular surgery with cardiopulmonary bypass | Cardiovascular surgery with cardiopulmonary bypass |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiovascular surgery with cardiopulmonary bypass | Procedure | Patients who underwent cardiovascular surgery including valve replacement or thoracic aortic surgery with cardiopulmonary bypass |
| Measure | Description | Time Frame |
|---|---|---|
| Acute kidney injury | acute kidney injury during postoperative seven days defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria | postoperative day seven |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause mortality | all-cause mortality after cardiovascular surgery after postoperative seven years | postoperative seven years |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative length of hospital stay | postoperative length of hospital stay | postoperative two month |
| Postoperative length of ICU stay | postoperative length of ICU stay during postoperative two months |
Inclusion Criteria:
Exclusion Criteria:
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adult patients who underwent cardiovascular surgeries with cardiopulmonary bypass (CPB), including valve replacement and surgery on the thoracic aorta at the Seoul National University Hospital between 2007 and 2015
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | Seoul | 03080 | South Korea |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| ID | Term |
|---|---|
| D013504 | Cardiovascular Surgical Procedures |
| D002315 | Cardiopulmonary Bypass |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
| D005112 | Extracorporeal Circulation |
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| postoperative two months |
| Postoperative incidence of complications | postoperative incidences of surgery-related complications during hospital stay | postoperative two months |
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |