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| Name | Class |
|---|---|
| Hawaa Fertility Center | OTHER |
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Cases which undergone ICSI before with failure of fertilization will do another ICSI cycle with removal of the polar body just before the ICSI procedure and sperm injection at the site of polar body removal. This study group will be evaluated with another group with the classic ICSI procedure
Patients with previous fertilization failure will be divided into 2 groups:
Group 1 (control): Will undergo classic ICSI procedure in half the MII oocyte of the same case.
Group 2 (study group): The other half of the MII oocyte of the same case will undergo:
Results: Will be collected with evaluation of number of 2PN zygotes, Day 1, Day 2, Day 3, Day 5 embryos in all the cases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| polar body removal | Experimental | polar body removal by zona drilling with laser then suction by injecting pipette then ICSI procedure is done |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| polar body removal using zona drilling by laser then suction by injecting pipette | Procedure | zona drilling with laser followed by polar body removal then ICSI procedure |
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| Measure | Description | Time Frame |
|---|---|---|
| fertilization rate of the zygotes | fertilization check is done under inverted microscopy by 2PN check | 16-20 hours post ICSI |
| Measure | Description | Time Frame |
|---|---|---|
| division rate of the embryos by the number of the blastomeres. | Detection of the number of the blastomeres and quality of the embryos under inverted microscopy. At day 5, detection of the rate of the blastocyst formation and quality of the embryos. | Day 2 & 3 & 5 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ahmed Saad | Benha University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Banha University- Hawaa Fertility center | Banhā | Qalyubia Governorate | 13512 | Egypt |
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| Classic ICSI | Procedure | Classic ICSI case was done be injecting sperm inside Oocyte while polar body is already existed at 6 or 12 O'clock position. |
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