Prospective, observational study at Stanford University Hospital comparing the Karius Infectious Disease Diagnostic Sequencing Assay to the Final Microbiologic Diagnosis in Patients with Fever and Neutropenia.

Inclusion Criteria:

• 18 years of age
• Are or will be admitted to Stanford University Hospital for fever and neutropenia
• Neutropenia - an absolute neutrophil count of <500 per cubic mm
• Documented fever or report of fever ≥38.3 or ≥38.0 on two episodes separated by at least one hour, resulting in hospitalization for febrile neutropenia

Exclusion Criteria:

• Inability to understand instructions and comply with study-related procedures
• Any condition that in the opinion of the treating physician will prevent the subject from completing the study

Patients who are admitted for fever and neutropenia at the Stanford University Hospital or patients who are admitted for chemotherapy who develop fever and neutropenia at Stanford University Hospital.