The age-associated loss of lean mass is a defining parameter of sarcopenia and may lead to various negative health outcomes such as impairment of physical performance and disability. Furthermore sarcopenia is considered to be one of the main factors in the pathogenesis of the frailty syndrome. However, for clinical use and for treatment and prevention strategies, reliable diagnostic criteria and cutpoints based on clinically relevant thresholds are indispensable.

This topic has recently been addressed by the Foundation for the National Institutes of Health Sarcopenia Project which identified cutpoints for appendicular lean mass (ALM) below which older adults had a higher likelihood of clinically relevant weakness reflected by low grip strength. Moreover, a low ALM-to-body mass index (BMI) ratio (<0.789 men and <0.512 women) was found to be associated with increased likelihood for mobility impairment.

In this context, the aim of this study is to study the prevalence of sarcopenia in a sample of community-dwelling frail and pre-frail older adults.

Inclusion Criteria:

• Aged 70 years and over,
• Living independently (ADL score ≥ 5/6),
• Fail or pre-frail according to Fried criteria,
• Informed written consent,
• Subjects affiliated to a social security.

Exclusion Criteria:

• Robusts patients (no Fried criteria),
• Other disorders that could interfere with the interpretation of the study (like visual or hearing impairments),
• Subjects under justice protection,
• Participation in another study at the same time.