Characteristics of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

Demographics, Clinical Characteristics, and Pathology of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

The purpose of this study is to investigate features of patients with Eosinophilic Gastrointestinal Disorders (EGIDs) other than Eosinophilic Esophagitis (EoE) alone, including Eosinophilic Gastritis (EG), Eosinophilic Gastroenteritis (EGE), and Eosinophilic Colitis (EC).

This retrospective chart review study will analyze the demographics, medical history, clinical features, and pathological data of patients with Eosinophilic Gastrointestinal Disorders (EGIDs) other than Eosinophilic Esophagitis (EoE) alone, including Eosinophilic Gastritis (EG), Eosinophilic Gastroenteritis (EGE), and Eosinophilic Colitis (EC).

Inclusion Criteria:

• Diagnosis of an EGID including EG, EGE, and/or EC. Subjects with EoE can be included if they also have another EGID.
• Clinical symptoms of gastrointestinal dysfunction.
• Findings of increased eosinophils on tissue biopsy at the time of diagnosis, before treatment initiated.
• Exclusion of other causes of gastrointestinal eosinophilia.

Exclusion Criteria:

• Gastrointestinal eosinophilia caused by another disorder.
• Diagnosis of EoE without another EGID.
• Insufficient medical record or pathology data available to support an EGID diagnosis.