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| Name | Class |
|---|---|
| Ministry of Health, China | OTHER_GOV |
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To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.
It is not clear whether femtosecond laser-assisted cataract surgery (FLACS) alters retinal and choroidal thickness. The goal of the present study was to determine the changes of retinal and choroidal thicknesses in patients who have undergone FLACS compared to patients who have undergone conventional phacoemulsification surgery (CPS).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| femtosecond laser-assisted cataract surgery group | Experimental |
| |
| conventional phacoemulsification surgery group | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Femtosecond laser-assisted cataract surgery | Procedure | A femtosecond laser (Alcon-Lensx, Alcon-Lensx, Inc.) was used in this study. After pupil dilation and topical anesthesia, the laser was docked to the eye using a curved contact lens to applanate the cornea. With the integrated OCT imaging system, the locations of the cornea and the anterior and posterior surfaces of the crystalline lens were determined. A 5.0-mm-diameter capsulotomy was created by scanning a cylindrical pattern and followed by lens fragmentation. The laser was disconnected, and the remainder of the surgery was performed as phacoemulsification (Infiniti® Vision System; Alcon, USA). Folded intraocular lenses (IOLs) were implanted in the capsular bags. |
| Measure | Description | Time Frame |
|---|---|---|
| The change of subfoveal choroidal thickness | The subfoveal choroidal thickness were measured at baseline and at 1 day, 7 days , 1 month , and 3 months postoperatively by spectral-domain optical coherence tomography. | baseline, at 1 day after surgery, 7 days after surgery, 1 month after surgery, and 3 months after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| The change of subfoveal retinal thickness | The subfoveal retinal thickness were measured at baseline and at 1 day, 7 days , 1 month , and 3 months postoperatively by spectral-domain optical coherence tomography. | baseline, at 1 day after surgery, 7 days after surgery, 1 month after surgery, and 3 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Haotian Lin, M.D., Ph.D | Zhongshan Ophthalmic Center, Sun Yat-sen University | Principal Investigator |
| Yizhi Liu, M.D., Ph.D | Zhongshan Ophthalmic Center, Sun Yat-sen University | Study Chair |
| Weirong Chen, M.D. | Zhongshan Ophthalmic Center, Sun Yat-sen University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongshan Ophthalmic Center, Sun Yat-sen University | Guangzhou | Guangdong | 510060 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26269445 | Background | Chen X, Xiao W, Ye S, Chen W, Liu Y. Efficacy and safety of femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract: a meta-analysis of randomized controlled trials. Sci Rep. 2015 Aug 13;5:13123. doi: 10.1038/srep13123. |
| Label | URL |
|---|---|
| Description Home page of Zhongshan Ophthalmic Center | View source |
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| ID | Term |
|---|---|
| D002386 | Cataract |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D014331 | Tropicamide |
| C005717 | proxymetacaine |
| ID | Term |
|---|---|
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Conventional phacoemulsification cataract surgery | Procedure | Phacoemulsification was performed through a temporal 3.2-mm clear corneal incision with the same machine and followed by IOLs implantation. |
|
| Tropicamide | Drug | After pupil dilation, 1 drop of tropicamide (0.5%) was applied every 15 minutes for 3 applications |
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| Proparacaine hydrochloride | Drug | topical anesthesia with proparacaine hydrochloride (0.5%) was applied. |
|
| Homepage of Childhood Cataract Program of the Chinese Ministry of Health(CCPMOH) | View source |