Detection in Peripheral Blood of Circulating Tumor Cells in Patient With Head and Neck Squamous Cell Carcinoma

The dissemination of individual tumor cells is a common phenomenon in solid cancers. Detection of tumor cells in peripheral blood circulating tumor cells (CTC) in nonmetastatic situation is of high prognostic significance.

The objective of our study was to detect circulating tumor cells in two different method in patient with head and neck squamous cell carcinoma .

Inclusion Criteria:

• Age ≥ 18 years
• Patient with head and neck squamous cell cancer stage III or IV histologically proven
• Patient naive to any prior therapy
• Patient with operate cancer and resectable tumor
• Hemoglobin ≥ 10g / dL
• Performance status ≤ 2
• Ability to provide written informed consent
• Patient's legal capacity to consent to study participation

Exclusion Criteria:

• Other previous histology tumors
• Medical conditions or acute or chronic severe psychiatric disorders
• Deprived of liberty or under supervision