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The biomarker study adds to our previous study on biomarkers in tear fluid. In this study the investigators examine wether the biomarker levels are in correlation with the disease level and duration of disease.
The questionnaire study focuses on the patients perspective. With a validated questionnaire fore keratoconus patient it examine the patients self.-evaluated visual challenges and quality of life
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| age 15-25 years | Ophthalmic examination, VA measure, contrast vision, pentacam measurement, Tear fluid, saliva and blood samples | ||
| age 25-35 years | Ophthalmic examination, VA measure, contrast vision, pentacam measurement, Tear fluid, saliva and blood samples | ||
| age 35-45 year | Ophthalmic examination, VA measure, contrast vision, pentacam measurement, Tear fluid, saliva and blood samples | ||
| > age 45 year | Ophthalmic examination, VA measure, contrast vision, pentacam measurement, Tear fluid, saliva and blood samples |
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| Measure | Description | Time Frame |
|---|---|---|
| Protein levels in tear fluid, saliva and blood(plasma) | fall 2018 | |
| Ranch analysis of questionnaire | fall 2018 |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with keratoconus residing in the Central Denmark Region
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| ID | Term |
|---|---|
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
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Tear fluid, saliva and blood.