decided not to go ahead with study at this time

The purpose of this investigator-initiated study is to determine whether the use of an accessory device called AmplifEYE can improve colonoscopy quality in patients who are undergoing average risk colorectal cancer screening. Primary end point is adenoma detection rates.

Inclusion Criteria:

• All adult patients greater than or at 50 years of age who are referred for average risk screening colonoscopy.

Exclusion Criteria:

• Any pregnant patient
• Patient's that are unable to provide consent for themselves
• Any patient undergoing diagnostic colonoscopy (IBD, rectal bleeding, recent change in bowel habits, etc.)
• Any patient undergoing surveillance (prior history of polyps or colorectal cancer)
• Any patient undergoing high risk screening colonoscopy (family history of colon cancer in first degree family member <65 years of age, or co-existing conditions that pre-dispose to colon cancer such as polyposis syndromes, PSC or IBD)
• Prior history of any cancer
• Current or past immunosuppression (due to either infection or medications)
• Coagulation disorder OR use of anti-coagulation or anti-platelet therapy other than aspirin within 5-7 days of procedure
• Colonic strictures
• suspected intestinal obstruction or colonic pseudo-obstruction
• history of colon resection
• active infection
• active inflammation (including diverticulitis)