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| Name | Class |
|---|---|
| Poitiers University Hospital | OTHER |
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Extubation is a crucial step when patients are being weaned from mechanical ventilator support. Indeed, the patient has to face an increasing burden imposed to the ventilation system. The ability to overcome this event will determine the patient survival. A warning signal could be very useful is this situation. 2 recent studies have shown that measuring diaphragmatic cupolas and muscular fibers thickening fraction could help to spot a population with a high risk of "diaphragmatic weakness", characterized by a high failure extubation rate. This study aims to verify that this kind of group of patients does exist.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single arm | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Diaphragmatic ultrasound | Procedure | All patients will have a diaphragmatic ultrasound in the 4 hours before the extubation.
|
| Measure | Description | Time Frame |
|---|---|---|
| Extubation success rate | Extubation success rate, defined as no reintubation 7 days after the reporting extubation | 7 days after the reported extubation |
| Measure | Description | Time Frame |
|---|---|---|
| Length of stay in reanimation unit (days) | At discharge of reanimation unit (up to 1 year) | |
| Length of mechanical ventilation | At the extubation time | |
| Number of patients with invasive or non-invasive mechanical ventilation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Saint Joseph Saint Luc | Lyon | 69007 | France | |||
| Centre Hospitalier Annecy Genevois |
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|
Resort to invasive or non-invasive mechanical ventilation |
| 48 hours after the extubation |
| Mortality | At discharge of reanimation unit (up to 1 year) |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a clinical parameter : cough strength measured with a defined scale | The scale used to measure the cough is the following :
| At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a clinical parameter : quantity of secretions measured with a defined scale |
| At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a clinical parameter : presence/absence or cervical tonus | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a clinical parameter : F/Vt ratio measured in breaths/min/L | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a paraclinical parameter : maximal inspiratory pressure in centimeters of water | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a paraclinical parameter : minimal expiratory pressure measured in centimeters of water | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a paraclinical parameter : peak flow measured in L/min (liters per minute) | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a paraclinical parameter : peak flow when coughing measured in L/min (liters per minute) | At the extubation time |
| Comparison between the predictive value of diaphragmatic ultrasound dysfunction and a paraclinical parameter : P0,1 measured in milliseconds | At the extubation time |
| Metz-Tessy |
| 74374 |
| France |
| Centre Hospitalier Universitaire de Poitiers | Poitiers | 86021 | France |