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Multiple studies have compared spinal anesthetic performed supine versus lateral, with varying results, in parturients having elective cesarean section. Needle positioning during spinal placement has also been examined. No positioning techniques have demonstrated definitive superiority for hemodynamic stability.
Investigators propose that following spinal placement in the sitting position if the patient is placed in a lateral position for 90 seconds prior to turning them supine, hemodynamic changes caused by sympathectomy related to the subarachnoid block can be avoided.
This is the first study to examining the influence of position changes after spinal anesthetic placement in the sitting position, which includes hemodynamic variables not previously studied including cardiac output, TPR (total peripheral resistance) and pulse pressure variation (PPV).
Cesarean section is chosen when natural spontaneous vaginal delivery is either not possible or when the health of the baby or mother is compromised. Cesarean section may be planned, urgent, or performed emergently when the life of the baby or mother is threatened.
Cesarean section is performed using different anesthetic techniques including: spinal, epidural, combined spinal and epidural, and general anesthesia. Spinal anesthesia is the most common technique chosen due to its relative safety, rapid onset and avoidance of potential complications from general anesthesia. It is the technique of choice for elective cesarean section unless contraindicated. Spinal anesthesia causes sympathetic blockade followed by sensory and motor blockade. Nerve fiber size explains the speed of onset and differential block. The critical moments during spinal anesthesia come as soon as local anesthetic is injected into the subarachnoid space.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Supine position | Sham Comparator | Supine position Supine position after placement of spinal anesthetic |
|
| Right lateral position | Active Comparator | Right lateral position Right lateral after placement of spinal anesthetic |
|
| Left lateral position | Active Comparator | Left lateral position Left lateral after placement of spinal anesthetic |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Supine position | Other | Spinal anesthesia in sitting position then 2 minutes in Supine position after spinal anesthetic administration |
|
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate | Continuous Heart rate (beats per minute) measurements. | Immediately before spinal anesthestic placement through placental delivery |
| Blood pressure | Continuous Blood pressure (mmHg) measurements | Immediately before spinal anesthetic placement through placental delivery |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of nausea and vomiting | Nausea and vomiting incidence and anti-emetic administration with time stamps will be documented. | Number of events spinal anesthetic placement through placental delivery |
| Anti-emetic medication |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ranganathan Govindaraj, MD, FRCA | The University of Texas Medical Branch, Galveston | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UTMB | Galveston | Texas | 77555 | United States |
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| ID | Term |
|---|---|
| D016683 | Supine Position |
| ID | Term |
|---|---|
| D011187 | Posture |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Right lateral position | Other | Spinal anesthesia in sitting position then 2 minutes in the right lateral position after spinal anesthetic administration |
|
| Left lateral position | Other | Spinal anesthesia in sitting position then 2 minutes in the left lateral position after spinal anesthetic administration |
|
Anti-emetic administration with time stamps will be documented.
| Number of events spinal anesthetic placement through placental delivery |
| Incidence of vasopressor usage | Number of vasopressor use events will be monitored and recorded. | Spinal anesthetic placement through placental delivery |
| Total vasopressor usage | All vasopressor administrations with time stamps will be documented. | Spinal anesthetic placement through placental delivery |
| Non Invasive Cardiovascular measurements: cardiac output | Continuous Cardiac output (L/min) measurements | Spinal anesthetic placement through placental delivery |
| Non Invasive Cardiovascular measurements: stroke volume | Continuous Stroke volume (mL) measurements | Spinal anesthetic placement through placental delivery |
| Non Invasive Cardiovascular measurements: TPR (total peripheral resistance) | Continuous TPR (total peripheral resistance, dynes*sec/cm3)measurements | Spinal anesthetic placement through placental delivery |