Iplasma IL6, Procalcitonin and VEGF and Dialysate Level in CAPD Patients

Interleukin-6, Procalcitonin and Vascular Endothelial Growth Factor in Plasma and Dialysate Correlate With Peritoneal Solute Transport and Dialysis Adequacy in CAPD Patients

The aim of study was to evaluated the correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.

This cross -sectional study measured IL-6, procalcitonin and VEGF level in plasma and overnight effluent. PSTR of small solutes was evaluated by standard peritoneal equilibration test (standard PET). Weekly Kt/V and creatinine clearance (CCr ) were evaluated in all patients.

Inclusion Criteria:

• Stable CAPD patients without previous history of peritonitis

Exclusion Criteria:

• HIV
• Other infections, tuberculosis or on immunosuppressive drugs,
• Autoimmune disease,
• Cancer
• Diagnosis of permanent ultrafiltration failure .