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The Ischemic Brain Vascular Accident (CVA) is a major public health issue. An Early and appropriate charging anyone with stroke is essential to reduce mortality, reduce dependency and promote recovery of autonomy. Intravenous fibrinolysis in patients with cerebral infarction (NINDS 1995), is reserved for a small proportion of highly selected patients. It therefore remains a significant therapeutic challenge, especially for patients with against-indications to fibrinolysis or in whom there is no immediate benefit. For twenty years of mechanical devices have been developed to remove, as quickly as possible, the cause of intracranial arterial occlusion and allow restoration of blood flow before brain damage is irreversible.
NTF The protocol is part of the evaluation process of our clinical practices recommended by the National Health Authority (HAS), in the specific context of mechanical thrombectomy performed in French centers of interventional neuroradiology working with neurovascular units (A V).
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| Measure | Description | Time Frame |
|---|---|---|
| clinical score for handicap (mRS) | at 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| hemorrhagic complications on postoperative imaging | baseline | |
| hemorrhagic complications on postoperative imaging | at 1 day | |
| physiological parameter : age |
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Inclusion Criteria:
Exclusion Criteria:
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200 consecutive patients admitted to a stroke unit for cerebral infarction treated by thrombectomy included (with or without fibrinolysis by intra venous) prospectively over a period of 1 year and 3 months followed for clinical neurological assessment (primary endpoint) .
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| Name | Affiliation | Role |
|---|---|---|
| Hubert DESAL, PU-PH | Nantes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Nantes | Nantes | 44093 | France |
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Factors of good clinical prognosis |
| baseline |
| presence of coronary artery disease | Factors of good clinical prognosis | baseline |
| presence of arterial hypertension | Factors of good clinical prognosis | baseline |
| presence of diabetes | Factors of good clinical prognosis | baseline |
| presence of hypercholesterolemia | Factors of good clinical prognosis | baseline |
| presence of intracranial stenosis | Factors of good clinical prognosis | baseline |
| presence of occlusive arterial disease | Factors of good clinical prognosis | baseline |
| presence of haematological disorders | Factors of good clinical prognosis | baseline |
| presence of neoplasia | Factors of good clinical prognosis | baseline |
| NIHSS score | Factors of good clinical prognosis | baseline |
| ASPECTS score | Factors of good clinical prognosis | baseline |
| MRI imaging of stroke | Factors of good clinical prognosis | baseline |
| unblocking rate based on the score TICI | at 3 months |
| NIHSS evaluation | at 24h |
| Influence of collaterality score on the NIHSS | at 24h |
| Influence ASPECTS score on the NIHSS | at 24h |
| Influence ASPECTS score on the NIHSS | at 3months |
| influence of anesthesia on the NIHSS | at 24h |
| hemorrhagic complications | at 24h |
| Influence of hemorrhagic complications on NIHSS | at 24h |
| Influence of hemorrhagic complications on NIHSS | at 3 months |