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Troponin T-us is a cardiac marker for myocardial infarction. Its use in neonates is increasing, yet normal values are still to be determined for the latest generation of tests, such as High sensitivity cardiac troponin T test. This study is an observational study designed to determine biological normal values of High sensitivity cardiac troponin T test (troponin T -us) in newborns.
Subjects have the right to withdraw from the study at any time for any reason. If one of the parents wishes to withdraw from the study after the first Troponin T measurement is made, we will ask for their permission to use the collected data.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Troponin T blood level | Biological | assess Troponin T blood level for every child born from the same sample of blood (after clamping the umbilical cord) used for assessment of pH and lactate. |
| Measure | Description | Time Frame |
|---|---|---|
| Level of cardiac high sensitive Troponin T in umbilical cord blood | T level will be analyzed by the biochemistry laboratory and collected by a study investigator. | At birth - Time 0 |
| Measure | Description | Time Frame |
|---|---|---|
| Noticeable events during pregnancy ; Delivery conditions | Any event, disease, treatment during pregnancy. Those data will be collected in the mothers pregnancy file. | Within the two hours following birth |
| Noticeable events in post partum |
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Inclusion Criteria:
Exclusion Criteria:
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Children born in hospital René Dubos
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| Name | Affiliation | Role |
|---|---|---|
| BORRHOMEE Suzanne, PH | suzanne.borrhomee@gmail.com | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH Rene Dubos | Pontoise | Val d'Oise | 95303 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10673613 | Background | Lefevre G. [Troponins: biological and clinical aspects]. Ann Biol Clin (Paris). 2000 Jan-Feb;58(1):39-48. French. | |
| 14971783 | Background | Adamcova M. Troponins in children and neonates. Acta Paediatr. 2003 Dec;92(12):1373-5. doi: 10.1080/08035250310007637. |
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Infection, jaundice… Those data will be collected in the baby's maternity file or intensive care unit file
| Before discharge |
| 16776629 | Background | Fortunato G, Carandente Giarrusso P, Martinelli P, Sglavo G, Vassallo M, Tomeo L, Rea M, Paladini D. Cardiac troponin T and amino-terminal pro-natriuretic peptide concentrations in fetuses in the second trimester and in healthy neonates. Clin Chem Lab Med. 2006;44(7):834-6. doi: 10.1515/CCLM.2006.144. |
| 21664586 | Background | Nomura RM, Ortigosa C, Fiorelli LR, Liao AW, Zugaib M. Gender-specific differences in fetal cardiac troponin T in pregnancies complicated by placental insufficiency. Gend Med. 2011 Jun;8(3):202-8. doi: 10.1016/j.genm.2011.05.001. |