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This study investigates the variations in the retinal nerve fiber layer (RNFL) thickness during uncomplicated anterior and intermediate uveitis, respectively. The objectives are to 1 ) confirm the RNFL thickening during an uncomplicated anterior uveitis as described in the literature, 2) measure the RNFL thickness during an uncomplicated intermediate uveitis specifically and 3) describe the variation in time of RNFL thickness during the two types of uveitis.
Thirty six individuals (18 with anterior uveitis and 18 with intermediate uveitis) will be recruited at the Centre universitaire d'ophtalmologie du CHU de Québec. RNFL thickness will be measured with optical coherence tomography at 3 times. For anterior uveitis, the RNFL thickness will be measured at presentation, 1 week and 4 to 6 weeks. For intermediate uveitis, the RNFL thickness will be measured at presentation, 4 to 6 weeks and 4 months. The initial thickness will be studied for each type of uveitis and progression over time will be studied also for each type of uveitis.
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| Measure | Description | Time Frame |
|---|---|---|
| Retinal Nerve Fiber Layer Thickness in anterior uveitis | At time 0 | |
| Retinal Nerve Fiber Layer Thickness in intermediate uveitis | At time 0 | |
| Change from Baseline Retinal Nerve Fiber Layer Thickness in anterior uveitis | at 4 to 6 weeks | |
| Change from Baseline Retinal Nerve Fiber Layer Thickness in intermediate uveitis | at 4 months |
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Inclusion Criteria:
Exclusion Criteria:
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Adult of 18 years old or more with anterior or intermediate uncomplicated uveitis
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| Name | Affiliation | Role |
|---|---|---|
| Simon Couture, Doctor | Centre de recherche du CHU de Québec : Université Laval | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre universitaire d'ophtalmologie, Hôpital du Saint-Sacrement. CHU de Québec | Québec | G1S 4LB | Canada |
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| ID | Term |
|---|---|
| D014606 | Uveitis, Anterior |
| D015867 | Uveitis, Intermediate |
| ID | Term |
|---|---|
| D015864 | Panuveitis |
| D014605 | Uveitis |
| D014603 | Uveal Diseases |
| D005128 | Eye Diseases |
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