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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00300-47 | Other Identifier | French Health Products Safety Agency |
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The investigators propose to carry out a prospective analysis of physical impact, psychological, cognitive and social of radiotherapy in all patients over 75 years bearer of localized prostate cancer with an indication of curative radiotherapy. This standardized geriatric assessment will collect social information, functional, sensory, cognitive, emotional, motor, nutritional, and medical related to comorbidities . The quality of life of patients will be evaluated by the QLQ C30 (Quality of Life Questionnaire) European Organisation for Research and Treatment of Cancer (EORTC) before starting treatment, at the end of radiotherapy (2 months) and at 6 months. This short follow-up period seems appropriate in this elderly population and will allow an answer within 2 years to the problem raised in clinical practice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| geriatric assessment and quality of life | Experimental | Included patient must have a geriatric assessment before radiotherapy and 6 months later. Patient must complete quality of life questionnaire before radiotherapy then 2 and 6 months later. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| geriatric assessment and quality of life | Other | Included patient must have a geriatric assessment before radiotherapy and 6 months later. This standardized geriatric assessment will collect social information, functional, sensory, cognitive, emotional, motor, nutritional, and medical related to comorbidities . Patient must complete quality of life questionnaire before radiotherapy then 2 and 6 months later. |
| Measure | Description | Time Frame |
|---|---|---|
| General tolerance of the radiotherapy evaluated by the QLQ-C30 questionnaire | Tolerance will be called bad for the loss of 20 or more points (out of 100) between the initial assessment and evaluations at 2 and 6 months. Tolerance will be called correct in other cases. This threshold of 20 points was selected according to the work of Osoba. | 2 months |
| Complete geriatric assessment | This standardized geriatric assessment will collect social information, functional, sensory, cognitive, emotional, motor, nutritional, and medical related to comorbidities . | 6 months |
| General tolerance of the radiotherapy evaluated by the QLQ-C30 questionnaire | Tolerance will be called bad for the loss of 20 or more points (out of 100) between the initial assessment and evaluations at 2 and 6 months. Tolerance will be called correct in other cases. This threshold of 20 points was selected according to the work of Osoba. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Aurore GOINEAU, MD | Institut de Cancerologie de l'Ouest | Principal Investigator |
| Stéphane SUPIOT, MD | Institut de Cancérologie de l'Ouest | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut de Cancérologie de l'Ouest | Angers | 49055 | France | |||
| Hopital Henri Mondor |
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|
| Radiotherapy | Radiation | standard radiotherapy |
|
| Créteil |
| 94000 |
| France |
| Centre Georges François Leclerc | Dijon | 21079 | France |
| CHD | La Roche-sur-Yon | 85925 | France |
| Centre Hospitalier Bretagne Sud | Lorient | 56100 | France |
| Centre Catherine de Sienne | Nantes | 44202 | France |
| Clinique Armoricaine de Radiologie | Saint-Brieuc | 22015 | France |
| CHP | Saint-Grégoire | 35760 | France |
| Clinique Mutualiste de l'Estuaire | Saint-Nazaire | 44606 | France |
| Institut de Cancérologie de Loire | Saint-Priest-en-Jarez | 42270 | France |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 22, 2026 |
| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
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| ID | Term |
|---|---|
| D015577 | Geriatric Assessment |
| D011788 | Quality of Life |
| D011878 | Radiotherapy |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D006304 | Health Status |
| D003710 | Demography |
| D011154 | Population Characteristics |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
| D013812 | Therapeutics |
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